PPT Slide

Corticosteroids in ARDs

RCT of 24 pts with ‘late’ ARDs
mortality (in hospital): 14% MPT vs. 65% (p=0.03)
Meduri GU, Headley S et al. Methylprednisolone treatment (MPT) of late ARDs. ALA/ATS 1997 Thematic Poster Session. Abstract Page: A391.
This study has subsequently been published and critical appraisal reveals a flaw in the design. Although the results are promising, due to the flaw (improper cross-over) a confirmatory trial is required.