PPT Slide

Analysis of cluster RCTs.

Given:

492 patient RCT. Mortality was reduced from 36% (82/223) to 24% (67/269).

Dead Alive Total

control 82 67.5 141 155.5 223

treated 67 81.5 202 187.5 269

149 149 343 343 492

?2 = Sum{[(Observed - Expected)2/ Expected] / Design Effect}

Design Effect (C) = 1+(m-1)?

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